Symbol
Name
ID

Kdm6a
lysine (K)-specific demethylase 6A
MGI:1095419

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Lateral ventricle dilatation

Hydrocephalus

Ventriculomegaly

Cerebral cortical atrophy

EEG abnormality

Dysarthria

Atypical behavior

Intellectual disability

Intellectual disability, mild

Global developmental delay

Seizure

Bilateral tonic-clonic seizure with focal onset

Focal impaired awareness seizure

Disease(s) Associated with KDM6A

Kabuki syndrome

Mouse Phenotypes		abnormal cranial neural crest cell morphology	abnormal neural tube closure	open neural tube	kinked neural tube	abnormal brain development	abnormal forebrain development	exencephaly
Availability	Mouse Genotype	abnormal cranial neural crest cell morphology	abnormal neural tube closure	open neural tube	kinked neural tube	abnormal brain development	abnormal forebrain development	exencephaly
	Kdm6a^{Gt(RRA094)Byg}/Kdm6a^{Gt(RRA094)Byg}
	Kdm6a^tm1.2Kaig/Kdm6a^tm1.2Kaig
	Kdm6a^{tm1b(EUCOMM)Jae}/Kdm6a^{tm1b(EUCOMM)Jae}
	Kdm6a^{tm1b(EUCOMM)Wtsi}/Kdm6a^{tm1b(EUCOMM)Wtsi}
	Kdm6a^{tm1c(EUCOMM)Wtsi}/Kdm6a^{tm1c(EUCOMM)Wtsi}
	Kdm6a^{Gt(RRA094)Byg}/Y
	Kdm6a^tm1.2Kaig/Y
	Kdm6a^{tm1b(EUCOMM)Wtsi}/Y
	Kdm6a^{tm1c(EUCOMM)Wtsi}/Kdm6a^{tm1c(EUCOMM)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)
	Kdm6a^{tm1c(EUCOMM)Wtsi}/Y H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)
	Kdm6a^{tm1a(EUCOMM)Jhha}/Kdm6a^{tm1b(EUCOMM)Jhha} Tg(Pgk1-cre)1Lni/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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